Who knows about 2012, but right now, TCU would obliterate anyone in the Big East. It's not even close.
As to the Big Ten, you know, it's bad enough to run the table in reverse. But to get run off the field by the likes of Mississippi State? That is so, so pathetic. I'm not a fan of firing coaches who win more games than they did they year before, but that was a fucking embarassment by Michigan.